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Title
Automation in Bioprocess Development: Near-, Mid-, and Long-Term Opportunities
Tuesday, January 08, 2019
Paul Denny-Gouldson
Claire Hill
Automation, combined with other technological advances such as the Internet of Things (IoT) and analytics platforms like?machine?learning,?will be a major part of the future of bioprocess development.
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Automation in the Drug Discovery Process: Delivering Analytical Chemistry to Biologists and Beyond
Friday, March 08, 2013
Wendy Gaisford
Over the past decade, advances in genomic- and proteomic-based research techniques and instrumentation have resulted in major breakthroughs in the elucidation of the structure and function of disease ...
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Best Practices for CO
2
Incubator Maintenance
Friday, July 22, 2016
Mary Kay Bates
The use of long-established mutant lines in culture has shifted, and it is common to find researchers using more sensitive stem cells, primary cells and 3-D cultures in applications including vaccine...
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Best Practices for the Use of Micropipets
Friday, June 13, 2014
A. Björn Carle
Doreen Rumery
George Rodrigues
Every day, air-displacement pipets are used to quantitatively dispense sample and reagent aliquots for reaction, routine analyses, and specialized tests.
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Cell Culture Advances Yield More Reliable Data for Cancer Research
Tuesday, July 26, 2016
James Lim
Cells stored with traditional culturing practices express different gene and protein profiles than their in vivo counterparts.
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Comparison of ICP-QQQ and MP-AES to Alternative Atomic Spectroscopy Techniques
Friday, February 17, 2017
Shane Elliott
This article gives an overview of the various atomic spectroscopy techniques available to address a range of applications in environmental science, food and agriculture, life sciences and academic ...
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Detection of siRNA-Mediated Gene Modulation Using RNA Detection Probes
Monday, May 20, 2013
Don Weldon
Grace Johnston
To study the function of genes and biological pathways, researchers often use techniques such as RNA interference (RNAi) to modify gene expression. In RNAi experiments, it is important to determine ...
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Electronic Pipetting: The Call for Innovation
Thursday, February 27, 2014
Paula Heimler
Take a close look around most laboratories and you will find an old, barely used fixture. No one knows who ordered it or who it belongs to. It is yellowed, dusty, and top heavy, with a small keyboard ...
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Electrophoresis 2.0: Faster, Stronger, and More Reproducible
Monday, August 04, 2014
Ryan Jensen
Stefan Lehr
Anton Posch
In 2010, researchers around the world were competing to finish the race to purify BRCA2, a protein whose mutant form is associated with more than 50% of hereditary breast cancer. But only one of ...
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Enabling Cancer Research and Treatment With Droplet-Based Digital PCR Technology
Wednesday, September 03, 2014
George Karlin-Neumann
Cancer research is as necessary as ever, especially if we are to fulfill the promise of personalized (or “precision”) medicine based on specific cancer therapies directed to known molecular targets.
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Examining the Multiple Parameters of Glycolytic Activity
Monday, September 28, 2015
Maya Dubey
Cellular energy enables vital activities such as proliferation, differentiation, stimuli response and intracellular signaling.
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For Accurate Cell-Based Assay Results, Transfer Technique Matters
Wednesday, November 09, 2016
John Lesnick
From smaller-scale assays to industrial-scale screening operations, cell-based assays are critical for applications that include elucidating basic mechanisms of cell function, target validation and ...
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Getting the Most Out of Limited Samples: A PCR Workflow for Monitoring Gene Expression
Tuesday, November 24, 2015
Joshua Fenrich
Seeking to identify the biochemical triggers that commit stem cells to distinct fates, researchers at the Lunenfeld-Tanenbaum Research Institute at Mount Sinai Hospital in Toronto assessed the culture...
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High-Throughput Drug Screening of Multicellular Tumor Spheroids
Tuesday, September 27, 2016
Ana Maria P. Pardo
Hannah J. Gitschier
David H. Randle
Terry Riss
Three-dimensional (3-D) culture models are increasingly being used for drug discovery in oncology, as they better represent the complexity of the in vivo microenvironment of solid tumors.
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How to Choose Between a CCD and sCMOS Scientific-Grade Camera
Wednesday, April 29, 2015
James Joubert
Cell biologists require microscopy tools that can detect rapid movements within a cell with detail and sensitivity in low light conditions. Developers must address performance requirements, and be ...
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How to Choose the Right Liquid Handling Automation Platform
Friday, January 11, 2019
Hal Wehrenberg
This article discusses some of the key points to consider when choosing a liquid handling platform for your laboratory.
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Identification of Cancer Stem Cells Within Mixed Populations Using Live Cell RNA Detection
Thursday, January 09, 2014
Don Weldon
Steve McClellan
Despite the ubiquity of studies measuring mRNA and miRNA levels, many current techniques require cell lysis and are enormously disruptive to the cells being studied.
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Improved Pipetting Technique: An “Out-of-the-Box” Solution to Reduce Manual Pipetting Errors
Monday, March 03, 2014
Tanya Knaide
Handheld air-displacement pipets are used in virtually every laboratory around the world. The technique and skills of individual pipet operators are critical to the accuracy of results of liquid ...
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In-House Pipette Calibration: The Lean Way
Thursday, October 08, 2015
A. Björn Carle
Sorenson Genomics of Salt Lake City focuses on DNA testing, with its expertise in quality, high-throughput testing that spans several diverse business units and highly accredited laboratories.
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Individual Cell Analysis for Protein Expression and Cell Health Markers
Tuesday, March 21, 2017
Robin T. Clark
The Muse instrument uses microcapillary fluidics and preoptimized reagents to create an inexpensive, compact, portable cell analyzer that requires minimal setup and no expertise to operate.
Read More
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